Yes, as long as the profit is known for Awesome Miner. Awesome Miner can use information from for example WhatToMine to know the profitability of a specific coin. For more information, see: Coin and profit statistics.

To add a single custom pool to the profit switcher, the first step is to add it as a new Pool in Awesome Miner via the Options dialog, Pools section. To use multiple pools, add all of them and then change to the Pool Groups tab where a new group can be added to include multiple pools.

To include a pool or a pool group to the profit switcher, go to the Options dialog, profit switching section and specify it as a Custom pool.