The easiest way to get started is to use the Profit Switcher, where Awesome Miner automatically select what to mine based on what is most profitable. Please see the guide Add Managed Profit Miners and profit switching using the Wizard.
An alternative, if you want to mine a specific coin or be in full control of the mining, is to select the mining software and mining pools yourself. Please see the guide Add Managed Miners using the Wizard.
When using multiple computers for mining, Awesome Miner main application should only be installed on a single computer and Awesome Miner Remote Agent application on all the other mining computers. For details, see the guide Getting started with GPU mining.