The Awesome Miner user interface requires Windows.  The Awesome Miner server is an optional component that can run either on Windows or Linux. The Remote Agent application used for Remote Proxy for ASIC miners and GPU/CPU mining can also run either on Windows and Linux.

For more details, see the guide Remote agent for Linux.

Awesome Miner can also connect to mining software already running on Linux - including software running on EthOS and HiveOS.